Biography of Frankie Rose

Photo of Frankie Rose
Full Title: Assistant Professor of Biology, PA Program Research Director
Building: Jorgensen Hall
Room Number: 321
Email: frrose [at] ucollege [dot] edu
Work Phone: 2364
Personal Phone: 402.957.1784
Departments: Division of Science and Mathematics - 402.486.2515, Physician Assistant Studies Program - 402.486.2527
Job Description:

Courses taught at Union:
Mammalian Physiology, Human Anatomy, Developmental Biology, Histology, Seminar in Biology, and Research Methods 3 and 4.

Academic Background

Postdoctoral Research, University of Missouri (2009-2010)

Field of Study: Development of gene therapy vectors for the treatment of Spinal Muscular Atrophy  (SMA)

Ph.D.  Microbiology, University of Missouri (2005- 2009)

Field of Study: Molecular Genetics of Spinal Muscular Atrophy (SMA)

Medical Student/Elective Research Studies, Kirksville College of Osteopathic Medicine (2002- 2005)

 

B.S. Biology, Union College (1997- 2002)

High School Diploma, Sunnydale Academy (1994-1997)

 

Publications:

Rose, F.F., Meehan, P.W., Coady, T.H., Garcia, V.B., Garcia, M.L., and Lorson, C.L. (2008). The Wallerian degeneration slow (Wlds) gene does not attenuate disease in a mouse model of spinal muscular atrophy. Biochemical and Biophysical Research Communications.

Ebert, A.D., Yu, J., Rose, F.F., Mattis, V.B., Lorson, C.L., Thomson, J.A., and Svendsen, C.N. (2009). Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 457, 277–280.

Rose, F.F., Mattis, V.B., Rindt, H., and Lorson, C.L. (2009). Delivery of recombinant follistatin lessens disease severity in a mouse model of spinal muscular atrophy. Hum. Mol. Genet. 18, 997–1005.

Butchbach, M.E.R., Rose, F.F., Jr, Rhoades, S., Marston, J., McCrone, J.T., Sinnott, R., and Lorson, C.L. (2010). Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. Biochem. Biophys. Res. Commun. 391, 835–840.

Glascock, J.J., Osman, E.Y., Coady, T.H., Rose, F.F., Shababi, M., and Lorson, C.L. (2011). Delivery of therapeutic agents through intracerebroventricular (ICV) and intravenous (IV) injection in mice. J Vis Exp.

Dale, J.M., Shen, H., Barry, D.M., Garcia, V.B., Rose, F.F., Lorson, C.L., and Garcia, M.L. (2011). The spinal muscular atrophy mouse model, SMAΔ7, displays altered axonal transport without global neurofilament alterations. Acta Neuropathol 122, 331–341.

Rindt, H., Buckley, D.M., Vale, S.M., Krogman, M., Rose, F.F., Jr, Garcia, M.L., and Lorson, C.L. (2012). Transgenic inactivation of murine myostatin does not decrease the severity of disease in a model of Spinal Muscular Atrophy. Neuromuscul. Disord. 22, 277–285.

Cobb, M.S., Rose, F.F., Rindt, H., Glascock, J.J., Shababi, M., Miller, M.R., Osman, E.Y., Yen, P.-F., Martin, B.R., Wetz, M.J., et al. (2013). Development and characterization of an SMN2-based intermediate mouse model of Spinal Muscular Atrophy. Hum. Mol. Genet.

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